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What is
diarrhea?

Diarrhea occurs when the body passes stool that is looser and more liquid-like than normal. These irregular bowel movements are due to one of two things: either more fluid is released into the intestines, or conversely, the intestines are instead struggling to absorb any liquid at all.

Acute vs. ChronicThere are two main types of diarrhea, acute and chronic.

Acute diarrhea is the most common form of diarrhea. It produces watery stool and does not last more than a few days. Most acute cases are caused by an infection (bacteria, viruses, or parasites) that attacks the gut. Other conditions may arise from non-infectious causes, where the problem develops due to medication or medical trauma.

Chronic diarrhea also produces inconsistent stool, but it lasts much longer. It is associated with certain conditions such as inflammatory bowel disease (IBD), celiac disease and irritable bowel syndrome (IBS). The symptoms and effects of chronic diarrhea are often more severe than acute diarrhea.

SymptomsWhile the stool's consistency is the main point in assessing the condition, it is not the only characteristic of diarrhea. Often there is an increase in the frequency of bowel movements, as well as how much stool is produced per sitting. But these symptoms are often meaningless if the stool's consistency remains normal. Additional symptoms may include a greater urgency to use the bathroom, blood or mucus appearing in the stool, feelings of abdominal discomfort, and dehydration (which will significantly intensify the severity of the diarrhea).

Although infrequent, some cases of diarrhea may require hospitalization and can have severe effects on the body. Diarrheal disease is in fact the second leading cause of death in children under five years old, mainly due to dehydration.

PrevalenceThere is an average of two billion cases of diarrheal disease every year, and the typical adult will encounter an episode of diarrhea about four times a year. Diarrhea can occur at any age, and in most cases it is treatable and short-lived.

What is
Saccharomyces boulardii?

For those suffering from diarrhea, rehydration is both the first and most important treatment for your symptoms. Saccharomyces boulardii from Biocodex may also help. Saccharomyces boulardii is a yeast-based probiotic that balances the naturally occurring bacteria that are located inside of your intestines. At the same time, it strengthens the intestinal immune system and restores normal bowel functions.

Treats and PreventsIn addition to oral rehydration solutions (ORS), Saccharomyces boulardii both treats and prevents diarrhea.

In cases of viral or bacterial types of acute diarrhea, Saccharomyces boulardii acts to effectively treat your condition along with ORS.

Saccharomyces boulardii's strain also prevents diarrhea that typically accompanies most antibiotic therapy, which is better known as antibiotic-associated diarrhea. Up to 30% of patients suffer from diarrhea during antibiotic treatment. Since Saccharomyces boulardii is the only probiotic drug with natural resistance to antibiotics, it allows you to continue and finish your treatment without the uncomfortable side effect of diarrhea.

Additionally, Biocodex Saccharomyces boulardii helps prevent recurrent diarrhea associated with Clostridium difficile. Saccharomyces boulardii also minimizes the effects of diarrhea related to numerous other conditions, such as diarrhea when traveling, known as travelers' diarrhea and irritable bowel syndrome.

ProofSb has been proven effective many times over. It is supported by more than 300 publications, including 90 pharmacological and 50 clinical studies, which confirm Saccharomyces boulardii's record of safety and success. Professional societies like ESPGHAN, NICE and numerous other leading experts in the field recommend Saccharomyces boulardii Biocodex for the management of all types of acute diarrhea.

LyophilizedSaccharomyces boulardii from Biocodex uses a unique strain that is lyophilized ? a method that processes ice directly into vapor, without melting it into a liquid state. The lyophilization process promises the strain's superior quality, vitality, and stability over time.

Place in MarketBiocodex Saccharomyces boulardii has been on the market for more than 50 years, longer than any other probiotic drug. Today, it is available in more than 100 countries. S. boulardii's success has earned the title of #1 probiotic drug worldwide in the treatment of diarrhea. Since it was first commercialized, Saccharomyces boulardii has reached to the top of the probiotic market in scientific evidence, global sales and coverage, years of experience and patients treated.

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Antibiotic-associated diarrhea (AAD)
Digestive Health Physician Li Ka Shing explains how the yeast probiotic Saccharomyces boulardii from Biocodex enables the restoration of good bacteria and reduces the risk of antibiotic associated diarrhea (AAD) by over 60% when taken simultaneously with antibiotics.
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Antibiotic-associated diarrhea (AAD)

Chan Kokfai (50), China

To counter the common symptoms such as severe coughing and high fevers, doctors frequently prescribe the antibiotic Amoxicillin ? often resulting in diarrhea. The case of Chan Kokfai was not different. After being admitted to hospital, his already weak state was intensified by antibiotic-associated diarrhea, prompting him to stop the medication. When his cough returned and he was forced to go back on the antibiotics, his doctor advised him to take the probiotic Bioflor (Saccharomyces boulardii from Biocodex) alongside the Amoxicillin. After just two days his diarrhea cleared up completely. He was able to complete his course of antibiotics and finally, his cough was gone.

Dr. Li Ka Shing, Digestive Health Physician, Beijing, China

Dr Li Ka Shing specialises in the digestive system. Like most doctors, he has to use antibiotics very often in his practice to cure a wide range of diseases. However, he is concerned about the high risk of associated diarrhea, caused by the destruction of beneficial bacteria in the intestine when antibiotics are taken. Here, Dr Li Ka Shing explains how the yeast probiotic Saccharomyces boulardii from Biocodex enables the restoration of good bacteria and reduces the risk of antibiotic associated diarrhea (AAD) by over 60% when taken simultaneously with antibiotics.

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S. boulardii

The No.1 probiotic drug worldwide

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Biocodex is an independent, global pharmaceutical company that was founded in 1953 in France by Michel Hublot and François Vallet. Biocodex was originally created for the production and marketing of Saccharomyces boulardii, a unique probiotic drug. Since then, Biocodex has expanded its range by developing more of its own products, as well as redeveloping products acquired from other companies. Biocodex now specializes in several therapeutic areas: Gastroenterology, Neurology, Psychiatry and Pain Treatment.

Today Biocodex strives to develop safe and effective products that improve the patient's health and quality of life. Biocodex makes sure that its products are available to the doctors and patients who need them. The company's progress relies on a commitment to the service of its patients and a close-knit relationship with doctors, pharmacists, and hospitals. Biocodex works towards the long term, while constantly improving its products with a clear and focused mindset. There are a total of 8 Biocodex offices stationed worldwide, with 3 sites in France and 5 subsidiary locations around the world. Today, Biocodex products are available in more than 100 countries around the world.

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